Rare Encephalitis in a European International StudentLife-Saving Turnaround Achieved in Beijing with Clinical Remission Spleen-Preserving Surgery

While studying in China, the student developed sudden-onset neuropsychiatric symptoms, including abnormal behavior, seizures, and altered consciousness. The condition was ultimately identified as a rare form of autoimmune encephalitis—anti-NMDA receptor encephalitis. After initial

evaluation and treatment in London, the patient showed no significant improvement, and the condition was regarded locally as a rare and complex

disease with no clearly effective treatment plan.

Facing persistent deterioration and a life-threatening condition, the patient learned that Peking Union Medical College Hospital is a leading national referral center for rare and complex diseases, with globally recognized diagnostic capabilities for difficult and undiagnosed conditions. The patient

subsequently sought care at the hospital’s International Medical Department for definitive diagnosis and treatment.

 

A multidisciplinary diagnostic approach was undertaken, including advanced neurological imaging and repeat cerebrospinal fluid analysis for anti-NMDA receptor antibodies. Following confirmation, second-line immunotherapy was promptly initiated, leading to a rapid reversal of the

critical condition and significant clinical improvement.

 

The patient’s neurological and psychiatric symptoms fully resolved, with complete recovery of cognitive and physical function, achieving clinical remission and a successful recovery outcome.